WHAT IS OTREXUP? (INDICATIONS)

OTREXUP is a single-dose auto-injector containing a prescription medicine, methotrexate.
Methotrexate is used to:

• Treat certain adults with severe, active rheumatoid arthritis (RA), and children with active polyarticular juvenile idiopathic arthritis (pJIA), after treatment with other medicines including non-steroidal anti-inflammatory drugs (NSAIDs) have been used and did not work well.
• Control the symptoms of severe, resistant, disabling psoriasis in adults when other types of treatment have been used and did not work well.

OTREXUP should not be used for the treatment of cancer.
OTREXUP should not be used for the treatment of children with psoriasis.